Denna studie har utvärderat effekterna, toleransen och acceptansen från vitlöksextrakt (aged garlic extract / AGE) som ett komplement till befintliga blodtryckssänkande läkemedel vid behandlad, okontrollerade hypertoni.
Studien var en dubbelblind, randomiserad, placebokontrollerad studie med 50 patienter. Patienterna fick 960 mg (2,4 mg S-allylcysteine) AGE dagligen alternativt att de fick placebotillskott. Hos de patienter som hade okontrollerad hypertoni (dvs över 140mm Hg), minskade det systoliska blodtrycket vid behandling med vitlök jämfört med de som endast fick placebo.
References:
1. Yusuf S, Sleight P, Pogue J, et al. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med. 2000;342:145-153.
2. Budoff MJ, Takasu J, Flores FR, et al. Inhibiting progression of coronary calcification using aged garlic extract in patients receiving statin therapy: a preliminary study. Prev Med. 2004;39:985-991.
3. Budoff MJ, Ahmadi N, Gul KM, et al. Aged garlic extract supplemented with B vitamins, folic acid and l-arginine retards the progression of subclinical atherosclerosis: A randomized clinical trial. Prev Med. 2009 49(2-3):101-107.
4. Naser A, Rezaeian P, Razipour A, et al. Aged garlic extract supplemented with B vitamins, folic acid and L-arginine reduce the progression of adipose tissue and coronary artery calcium. Circulation. 2010:122;A20824.
5. Gohar F, Greenfield SM, Beevers DG, Lip GY, Jolly K. Self-care and adherence to medication: a survey in the hypertension outpatient clinic. BMC Complement Altern Med. 2008;8:4.
6. Turnbull F. Blood Pressure Lowering Treatment Trialists Collaboration. Effects of different blood pressure lowering regimens on major cardiovascular events: results of prospectively designed overviews of randomized trials. Lancet. 2003;362:1527-1535.
Källa: Natural Medicine Journal
www.kosttillskott-guiden.net
www.naturmedicin-guiden.se
www.kostkoll.se